What is the Fasting Mimicking Diet?

Fasting Mimicking Diet

What is the Fasting Mimicking Diet?

The first and only patented nutrition program to support healthy aging through cellular rejuvenation.

Fasting benefits — without the water-only fast

The Fasting Mimicking Diet (FMD)

Fasting benefits — without the water-only fast

A revolutionary five-day nutrition program scientifically formulated to mimic the effects of a prolonged water fast while still allowing nourishment — supporting the benefits of fasting without the challenges and risks that come from water-only fasts.

From the pioneers in longevity science

Prolon is the only nutrition program patented for supporting longevity, healthspan, and protecting lean body mass through cellular rejuvenation.

25+

Years of scientific research

Decades of studies on longevity and nutrition

47

Clinical trials

Conducted with world-leading institutions

18

Leading research institutions

Including USC, Stanford, Mayo Clinic, and more

200+

Pending or issued patents

For optimizing longevity and healthspan

Autophagy ends with a full reprogramming of new cells. When you reprogram, you are impacting the DNA. We are reprogramming the cells to behave younger.

Dr Joseph Antoun, MD, PhD

L-Nutra's CEO

Five days that build on one another

How does FMD work?

Five days that build on one another

Each day of the Prolon fast is carefully formulated to activate your body's natural cell-rejuvenating processes. The five days build upon one another to trigger the various stages of fasting that contribute to cellular renewal.

Typically by day 2 the body enters ketosis, burning fat for fuel, and by day 3, autophagy kicks in — your body's natural process of recycling or removing damaged cells. It continues throughout the rest of your fast, and the FMD's effects may go beyond autophagy to support complete cellular reprogramming.

Five days of plant-based nutrition

What's in the box

Five days of plant-based nutrition

Every Prolon kit includes everything you need for a complete five-day cycle:

  • Soups
  • Nut Bars
  • Snacks
  • L-Drink
  • Supplements
  • Herbal Teas

The science behind your FMD

Two phases of cellular renewal

Phase 1

Autophagy

Autophagy, the first phase of rejuvenation, begins around day 3 of the FMD. During this process, the body clears out damaged cellular components, recycling essential materials and preparing for renewal.

Phase 2

Cellular reprogramming

Following autophagy, new, healthier cells emerge, reprogrammed to function more efficiently. This cellular reset impacts DNA, promoting a youthful cellular profile that can support healthy aging and a healthy immune system.

One program. Many benefits.

A single five-day program that supports your body in more ways than one.

Fat-focused weight loss

Improved skin health & radiance

Mental clarity & focus

Healthy aging through cellular rejuvenation

Renewed energy

Metabolic reset

Start your journey with Prolon today

Get started

Start your journey with Prolon today

Experience the scientifically proven way to receive the rejuvenating effects of fasting while receiving essential nutrition. Thousands have already discovered the power of Prolon's FMD — science-backed and designed for real results.

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Dr. Valter Longo, Ph.D

The creator of Fasting Mimicking Technology

Dr. Valter Longo, Ph.D

Dr. Valter Longo, Director of the Longevity Institute at the University of Southern California, was recognized by TIME as one of the top 50 most influential people in health. As the pioneering mind behind the Fasting Mimicking Diet, Dr. Longo was awarded the first-ever patent for Healthspan.

His groundbreaking work revealed how cells sense nutrients, leading him to develop the FMD formulation. Through extensive mouse and human trials, he demonstrated the powerful benefits of this approach — the foundation of the Prolon product line.

Read his story